Rectal suppositories "Indomethacin" - a preparation,related to the NSAID group. It has antipyretic activity, analgesic and anti-inflammatory effect. The drug has a depressing effect on cyclooxygenase, which leads to a disruption in the synthesis of arachidonic acid and prostaglandins. The drug helps to inhibit the aggregation of platelets. The medication weakens the pain syndrome, especially pain and stiffness in the joints in the morning, at rest and during movement. Against the background of local use, puffiness decreases and erythema decreases. Anti-inflammatory effect develops after the first week of application.
Indomethacin candlesrecommends with pain in the spine, articular syndrome. In particular, the indications include gout, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis. The medication is prescribed for dysmenorrhea, traumatic inflammation in the joints and soft tissues, myalgia, neuralgia. As an auxiliary, the drug is recommended for cystitis, prostatitis.
How to apply Indomethacin candles
Suppositories are injected deep into the rectum. Before the introduction, hygiene procedures should be carried out. Candles "Indomethacin" instruction for use recommends using after the therapy by intramuscular injection of the drug. Dosage of 50-100 mg / day. It is recommended to use the drug at night. In severe pathologies, the dosing regimen is determined personally. The maximum dose per day is 200 mg.
Candles "Indomethacin". Instructions for use. Adverse Reactions
Due to the local use of the medicineare most often allergic reactions to mucous membranes and skin, itching in the anorectal area, irritation. Rarely, rectal involvement, bleeding from the gastrointestinal tract, exacerbation of chronic colitis are rare.
Candles "Indomethacin". Instructions for use. Contraindications
The drug is not recommended for erosive ulcersdamage to the gastrointestinal system, hypersensitivity. Contraindications include a disorder of the liver or kidneys, pancreatitis in severe form, pregnancy. Do not prescribe medication with recent bleeding from the rectum, in children up to fourteen years old, with proctitis, cracks or other injuries to the anus.
Caution is observed in the treatment of the elderlypatients, if the patient has renal or hepatic pathologies, history of the gastrointestinal tract, arterial hypertension, dyspeptic manifestations during use. Dose adjustment may be required for epilepsy, cardiovascular disorders, immediately after surgery. If there is anamnestic data on intolerance to NSAIDs, the drug is allowed only in emergency situations. It is not recommended to use the medication simultaneously with acetylsalicylic acid. On the background of therapy should provide control over the condition of the picture of peripheral blood, the activity of the liver and kidneys.